Take a squirt gun into the rest room stall next to someone and shoot little drops over the wall every couple of seconds while pretending to pee.
 740
0  

Install the Blue Screen of Death screen-saver on someone's computer.
 803
3  

Write a message on an upside-down paper cup that alludes to something horrible being trapped under it. Leave it on a coworker's desk or in a conference room.
 1440
1  

Hide all of the desktop icons on someone's computer and replace the monitor's wallpaper with a screen-shot of their desktop.
 872
0  

Put tape over the optical sensor of someone's mouse.
 839
1